Name：De-Qun Wu
Title：Associate Professor
Tel：+86-21-6779-2380
Office：School of Textile, 4044
Email:dqwu@dhu.edu.cn
Background
- 2004- 2009, Master and Ph.D, Department of Chemistry, Wuhan University, China
- 2009, Postdoctoral Associate, Nanyang Technological University, Singapore
- 2010- 2013, Postdoctoral Associate, Cornell University, USA.
- 2013- Associate Professor, Donghua University, Shanghai, China
Researching Field
- Biomedical and textile materials
- Natural fiber modification
- Assembly of biodegradable materials and controlled drug carriers
- Nanomaterials based sensor
Awards
- 2014 Shanghai Pujiang Program, 14PJ1400300
- 2014 Textile Industry Federation First Prize for scientific and technological progress
Researching Project within five years
2014 Shanghai Pujiang Program, 14PJ1400300
Papers & Patents within five years
Papers
1. Wu DQ, Sun YX, Xu XD, Cheng SX, ZhangXZ, and Zhuo RX. Biodegradable and pH-sensitive hydrogels for cell encapsulation and controlled drug release. Biomacromolecules 2008,9:1155-1162.
2. Wu DQ, Wang T, Lu B, Xu XD, Cheng SX, Jiang XJ, ZhangXZ, Ren-Xi Zhuo. Fabrication of supramolecular hydrogels for drug delivery and stem cell encapsulation. Langmuir 2008,24:10306-10312.
3. Wu DQ, Lu B, Chang C, Chen CS, Zhang YY, Cheng SX, Zhang XZ, Zhuo RX. Galactosylated fluorescent labeled micelles as a liver targeting drug carrier. Biomaterials. 2009,30:1363-1371.
4. Wu DQ, Qiu F, Wang T, Zhang XZ, Zhuo RX. Towards development of partially biodegradable and injectable thermoresponsive hydrogels for potential biomedical applications. ACS Applied materials & interfaces. 2009,1:319-327.
5. Wu DQ, Li ZY, Fan JJ, Cheng SX, Jiang XJ, ZhangXZ, Ren-Xi Zhuo. Porphyrin and Galactosyl Conjugated Micelles for Targeting Photodynamic Therapy. Pharmaceutical Research, 2010, 27:187-199.
6. Dequn Wu, Jun Wu, Chi-Chang Chu. A Novel Family of Biodegradable Hybrid Hydrogels from Arginine-based Poly(ester amide) and Hyaluronic Acid Precursors. Soft matter. 2013, DOI: 10.1039/c3sm27820d.
7. Jun Wu, Dequn Wu, Martha A. Mutschler, and Chih-Chang Chu, Cationic Hybrid Hydrogels from Amino Acid-Based Poly (ester amide): Fabrication, Characterization, and Biological Property.Advanced Functional Materials. 2012,22,3815-3823.
8. Xiao-Hong Qin, De-Qun Wu, Chih-Chang Chu. Dual functions of polyvinyl alcohol (PVA): fabricating particles and electrospinningnanofibers applied in controlled drug release. Journal of Nanoparticle Research. 2013,15:1395-1409.
9.Lu B,Wu DQ,Zheng H,Quan CY,Zhang XZ, Zhuo RX.Galactosyl conjugated N-succinyl-chitosan-graft-polyethylenimine for targeting gene transfer.Molecular Biosystems, 2010, 6, 2529-2538.
10.Xun W, Wu DQ, Li ZY, Wang HY, Huang FW, Cheng SX, Zhang XZ, ZhuoRX.Peptide-Functionalized Thermo-Sensitive Hydrogels for Sustained Drug Delivery. Macromolecular bioscience. 2009, 12, 1219-1226.
11. Quan CY, Wu DQ, Chang C, Zhang GB, ChengSX, Zhang XZ, Zhuo RX. Synthesis of thermo-sensitive micellar aggregates self-assembled from biotinylated PNAS-b-PNIPAAm-b-PCL triblock copolymers for tumor targeting. Journal of Physical Chemistry C. 2009, 113:11262-11267.
12. Wang T, Wu DQ, Jiang XJ, Li XY, Zhang JF, Zheng ZB, Jiang H, Huang CX, Zhang XZ. Novel thermosensitive hydrogel injection inhibits post-infarct ventricle remodeling. European Journal of Heart Failure. 2009, 11:14-19.
13. Lu B, Wang CF, Wu DQ, Li C, Zhang XZ, Zhuo RX. Chitosan based oligoamine polymers: synthesis, characterization, and gene delivery. Journal of Controlled Release. 2009,137:54-62。
14. Hu CH, Zhang L, Wu DQ, Cheng SX , Zhang XZ, Zhuo RX. Heparin-modified PEI encapsulated in thermosensitive hydrogels for efficient gene delivery and expression. Journal of materials chemistry. 2009,19:3189-3197.
15. Qin XH, Wu DQ. Effect of different solvents on poly(caprolactone) (PCL)electrospun nonwoven membranes. Journal of Thermal Analysis andCalorimetry, 2011, 102, 1-7.
16. Chang C, Wei H, Feng J, Wang ZC, Wu XJ, Wu DQ, Cheng SX, Zhang XZ, and ZhuoRX.Temperature and pH Double Responsive Hybrid Cross-Linked Micelles Based on P(NIPAAm-co-MPMA)-b-P(DEA): RAFT Synthesis and “Schizophrenic” Micellization. Macromolecules 2009,42:4838-4844.
17. Zhang J, Xu XD, Wu DQ, Zhang XZ, Zhuo RX. Synthesis of thermosensitiveP(NIPAAm-co-HEMA)/cellulose hydrogels via “click” chemistry. Carbohydrate Polymers. 2009,77:583–589.
18. Qiu F, Feng J, Wu DQ, Zhang XZ, Zhuo RX. Nanosized Micelles Self-Assembled from amphiphilic dextran-graft-methoxypolyethylene glycol/poly(epsilon-caprolactone) copolymers. European Polymer Journal. 2009, 45:1024-1031.
19. Wang T, Jiang XJ, Tang QZ, Li XY, Lin T, Wu DQ, Zhang XZ, Okello E. Bone marrow stem cells implantation with a-cyclodextrin/MPEG–PCL–MPEG hydrogel improves cardiac function after myocardial infarction. ActaBiomaterialia. 2009, 5: 2939-2944.
20. Wei H, Wu DQ, Li Q, Cheng SX, ZhangXZ, and Zhuo RX. Preparation of shell cross-linked thermoresponsive hybrid micelles as well as hollow spheres based on P(NIPAAm-co-HMAAm-co-MPMA)-b-PCL. Journal of physical chemistry C. 2008, 112:15329.
21. Qin XH, Wu DQ. Effect of different solvents on poly(caprolactone) (PCL)electrospun nonwoven membranes. Journal of Thermal Analysis andCalorimetry, 2011, 102, 1-7.
22. Li XY, Wang T, Jiang XJ, Lin T, Wu DQ, Zhang XZ. Injectable Hydrogel Helps Bone Marrow-Derived Mononuclear Cells Restore Infarcted Myocardium. Cardiology. 2010, 115,194-199.
23. Wang T, Jiang XJ, Tang QZ, Li XY, Lin T, Wu DQ, Zhang XZ, Okello E. Bone marrow stem cells implantation with a-cyclodextrin/MPEG–PCL–MPEG hydrogel improves cardiac function after myocardial infarction. ActaBiomaterialia. 2009, 5: 2939-2944.
24.Jun Wu, Xin Zhao, Dequn Wu and Chih-Chang Chu.Development of a biocompatible and biodegradable hybrid hydrogel platform for sustained release of ionic drugs.J. Mater. Chem. B, 2014,2, 6660-6668.
Patent
Chinese Patent:
Xian-zheng Zhang, De-qun Wu, Ren-Xi Zhuo. Preparation and application of biodegradable and temperature sensitive hydrogel. Application number: 200810048486.0
US Patent:
1. Chu Chih-Chang, Wu De-Qun. Advanced Generation Lysine-based Multifunctional Poly(ester amide)s. D-5447
2.Chu Chih-Chang, Wu De-Qun. Peptide-based Poly(ester amide)s D-5400
3. Chu Chih-Chang, Wu De-Qun, He Mingyu. Polysaccharide-based hydrogels and hybrid hydrogels and precursors thereof, methods of making same, and uses thereof. Publication number: WO2013/181566
4. Chu Chih-Chang, Qin Xiao-Hong, Wu De-Qun. Fabrication of SyntheticBiodegradable Amino Acid Poly(ester amide)s Nanoparticles . D-5597
